Pharmahof Glizide Dosage & Drug Information

Concise Prescribing Info

Contents

Glipizide

Indications/Uses

Maturity-onset diabetes not manageable by diet alone.

Dosage/Direction for Use

Initially ½ to 1 tab daily. Max dose: 8 tab daily in 2 divided doses.

Administration

Should be taken on an empty stomach: Take 30 min before meals.

Contraindications

Hypersensitivity. Type II DM w/ ketoacidosis & type 1 DM.

Special Precautions

Increased risk of hypoglycemia. Renal or hepatic impairment. Not recommended during pregnancy & lactation.

Adverse Reactions

GI disturbances eg, nausea, vomiting, heart burn, anorexia, diarrhoea; skin rashes, pruritus, photosensitivity, hypoglycemic coma, cholestatic jaundice, leucopenia, thrombocytopenia, agranulocytosis & hemolytic anemia.

View ADR Monitoring Form

Drug Interactions

Increased hypoglycemic effect w/ anabolic steroids; ACE inhibitors; H₂ antagonists, antacids, oral Na bicarbonate. Increased levels/effects w/ CYP2C8/9 inhibitors eg, delavirdine, fluconazole, gemfibrozil, ketoconazole, nicardipine, NSAIDs, pioglitazone, sulfonamides. Increased serum conc w/ cyclosporine; tacrolimus. Decreased hypoglycemic effect w/ β-blockers; ethanol; rifampin. Decreased absorption w/ cholestyramine. Decreased levels/effects w/ CYP2C8/9 inducers eg, carbamazepine, phenobarb, phenytoin, rifampin, rifapentine, secobarbital. Hyperglycemia w/ corticosteroids.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BB07 - glipizide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Thai FDA Category

Presentation/Packing

Form

Glizide tab 5 mg

Packing/Price

100 × 15's;5 × 15's

Pharmahof Glizide

glipizide

Manufacturer:

Pharmahof

Distributor:

Pharmahof